Recombinant Proteins

The WCBF can produce recombinant proteins from a wide variety of bacterial or mammalian host cells.   Downstream processing capabilities include column chromatography, refolding, tangential flow filtration, and microfiltration, all using scalable processes.

No matter what type of process you are starting with, by utilizing the WCBF, your recombinant protein therapeutic can be produced using a reproducible and scalable method that meets industry standards for FDA submission.

Fermentation / Cell Culture Capabilities

30 Liter steam in place fermentor
36 liter bioreactor for suspension cells
Mutitray Cell Factories for attachment dependent cells

Downstream Purification Capabilities

Cell harvest by continuous centrifugation or filtration
Cell lysis
Supernatat concentration / buffer exchange
Column Chromatogrpahy
Refolding (100 liter chilled tank)
TFF/ultrafiltration